Endocrine Abstracts

Long acting somatostatin analogues (SMS) are extensively used as second and even first line treatment of acromegaly. Except of the inhibition of GH secretion, somatostatin is a potent inhibitor of insulin secretion from the pancreatic b- cells. As defects of glucose homeostasis are very common in acromegaly, we decided to examine the effect of the control of GH hypersecretion with SMS on glucose metabolism.We study 44 acromegalic patients divided in 3 gr...

Generously supported by IPSEN)-->Endogenous hypercortisolism leads to increased morbidity and mortality. As Cushing’s disease (CD) is a rare disorder, data on co-morbidities outcome after current treatment interventions are scarce.We studied 78 patients with CD (67 females, 11 males, mean age 42.2±1.4 years), with a follow up of 90.8±7.8 months. All patients underwent transsphenoidal surgery (TSS...